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1

Guava fruit extract and its triterpene constituents have osteoanabolic effect: Stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/β-catenin signaling

Porwal, Konica, Pal, Subhashis, Dev, Kapil, China, Shyamsundar Pal, Kumar, Yogesh, Singh, Chandan, Barbhuyan, Tarun, Sinha, Neeraj, Sanyal, Sabyasachi, Trivedi, Arun Kumar, Maurya, Rakesh, Chattopadhy

Journal:

The Journal of Nutritional Biochemistry

Year:

2017

Language:

english

File:

PDF, 1.71 MB

english, 2017

2

In silico screening of hundred phytocompounds of ten medicinal plants as potential inhibitors of nucleocapsid phosphoprotein of COVID-19: an approach to prevent virus assembly

Rolta, Rajan, Yadav, Rohitash, Salaria, Deeksha, Trivedi, Shubham, Imran, Mohammad, Sourirajan, Anuradha, Baumler, David J., Dev, Kamal

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2020

File:

PDF, 4.50 MB

2020

3

Solution structures of cyclic melanocortin agonists and antagonists by NMR

Jinfa Ying, Katalin E. Kövér, Xuyuan Gu, Guoxia Han, Dev B. Trivedi, Malcolm J. Kavarana, Victor J. Hruby

Journal:

Year:

2003

Language:

english

File:

PDF, 505 KB

english, 2003

4

Cell Signaling and Trafficking of Human Melanocortin Receptors in Real Time Using Two-photon Fluorescence and Confocal Laser Microscopy: Differentiation of Agonists and Antagonists

Minying Cai, Eva V. Varga, Magda Stankova, Alexander Mayorov, Joseph W. Perry, Henry I. Yamamura, Dev Trivedi, Victor J. Hruby

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

5

Corrigendum to “Guava fruit extract and its triterpene constituents have osteoanabolic effect: stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/β-catenin signalling” [ J Nutr Biochem (2017) 44; 22–34]

Porwal, Konica, Pal, Subhashis, Dev, Kapil, China, Shyamsundar Pal, Kumar, Yogesh, Singh, Chandan, Barbhuyan, Tarun, Sinha, Neeraj, Sanyal, Sabyasachi, Trivedi, Arun Kumar, Maurya, Rakesh, Chattopadhy

Journal:

The Journal of Nutritional Biochemistry

Year:

2017

Language:

english

File:

PDF, 222 KB

english, 2017

6

Opioid and melanocortin receptors: Do they have overlapping pharmacophores?

Yeon Sun Lee, Richard S. Agnes, James P. Cain, Vinod Kulkarni, Minying Cai, Christine Salibay, Kathy Ciano, Ravil Petrov, Alexander Mayorov, Josef Vagner, Dev Trivedi, Peg Davis, Shou-wu Ma, Josephine

Journal:

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

7

Design and Synthesis of Novel χ2-Constrained Phenylalanine, Naphthylalanine, and Tryptophan Analogues and Their Use in Biologically Active Melanotropin Peptides.

Wei Wang, Minying Cai, Chiyi Xiong, Junyi Zhang, Dev Trivedi, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 254 KB

2003

8

Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors

James P. Cain, Alexander V. Mayorov, Minying Cai, Hui Wang, Bahar Tan, Kevin Chandler, YeonSun Lee, Ravil R. Petrov, Dev Trivedi, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

9

Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors

Alexander V. Mayorov, Minying Cai, Erin S. Palmer, Dustin K. Tanaka, James P. Cain, Matthew M. Dedek, Bahar Tan, Dev Trivedi, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 360 KB

english, 2011

10

Design and synthesis of novel χ2-constrained phenylalanine, naphthylalanine, and tryptophan analogues and their use in biologically active melanotropin peptides

Wei Wang, Minying Cai, Chiyi Xiong, Junyi Zhang, Dev Trivedi, Victor J Hruby

Journal:

Year:

2002

Language:

english

File:

PDF, 482 KB

english, 2002

11

[des His1, des Phe6, Glu9]glucagon amide: A newly designed “pure” glucagon antagonist

Bassem Y. Azizeh, Brian A. Van Tine, Noel S. Sturm, Ann Marie Hutzler, Clinton David, Dev Trivedi, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 245 KB

english, 1995

12

Structure-activity studies of hydrophobic amino acid replacements at positions 9, 11 and 16 of glucagon

NOEL S. STURM, ANN MARIE HUTZLER, CLINTON S. DAVID, BASSEM Y. AZIZEH, DEV TRIVEDI, VICTOR J. HRUBY

Journal:

Chemical Biology & Drug Design

Year:

1997

Language:

english

File:

PDF, 630 KB

english, 1997

13

Effects of Macrocycle Size and Rigidity on Melanocortin Receptor-1 and -5 Selectivity in Cyclic Lactam α-Melanocyte-Stimulating Hormone Analogs

Alexander V. Mayorov, So-Yeop Han, Minying Cai, Matthew R. Hammer, Dev Trivedi, Victor J. Hruby

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

14

Exploring the Stereostructural Requirements of Peptide Ligands for the Melanocortin Receptors

VICTOR J. HRUBY, MINYING CAI, PAOLO GRIECO, GUOXIA HAN, MALCOLM KAVARANA, DEV TRIVEDI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 741 KB

2003

15

Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism

J.Adolfo Garcái-Sáinz, Marina Macías-Silva, S.M.Teresa Hernández-Sotomayor, Ma.Eugenia Torres-Márquez, Dev Trivedi, Victor J. Hruby

Journal:

Cellular Signalling

Year:

1990

Language:

english

File:

PDF, 641 KB

english, 1990

16

Design of novel melanocortin receptor ligands: Multiple receptors, complex pharmacology, the challenge

Victor J. Hruby, Minying Cai, James Cain, Joel Nyberg, Dev Trivedi

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 521 KB

english, 2011

17

Importance of the C-terminal α-helical structure for glucagon's biological activity

JOHN L. KRSTENANSKY, CHRISTIAN ZECHEL, DEV TRIVEDI, VICTOR J. HRUBY

Journal:

Chemical Biology & Drug Design

Year:

1988

Language:

english

File:

PDF, 520 KB

english, 1988

18

Synthetic glucagon antagonists and partial agonists

CHRISTIAN ZECHEL, DEV TRIVEDI, VICTOR J. HRUBY

Journal:

Chemical Biology & Drug Design

Year:

1991

Language:

english

File:

PDF, 706 KB

english, 1991

19

Synthetic linear and cyclic glucagon antagonists

RAMALINGA DHARANIPRAGADA, DEV TRIVEDI, ANNE BANNISTER, MARA SIEYEL, DIRK TOURWE, NEVENA MOLLOVA, KARL SCHRAM, VICTOR J. HRUBY

Journal:

Chemical Biology & Drug Design

Year:

1993

Language:

english

File:

PDF, 881 KB

english, 1993

20

Intramedullary sodium cyanide injection on respiratory and vasomotor responses in cats

J. Mitra, N.B. Dev, R. Trivedi, S. Amini, P. Ernsberger, N.S. Cherniack

Journal:

Respiration Physiology

Year:

1993

Language:

english

File:

PDF, 632 KB

english, 1993

21

Cardiorespiratory changes induced by vertebral artery injection of sodium cyanide in cats

J. Mitra, N.B. Dev, J.R. Romaniuk, R. Trivedi, N.R. Prabhakar, N.S. Cherniack

Journal:

Respiration Physiology

Year:

1992

Language:

english

File:

PDF, 736 KB

english, 1992

22

Comparative transcriptome analysis of arsenate and arsenite stresses in rice seedlings

Debasis Chakrabarty, Prabodh Kumar Trivedi, Prashant Misra, Manish Tiwari, Manju Shri, Devesh Shukla, Smita Kumar, Arti Rai, Ashutosh Pandey, Deepti Nigam, Rudra Dev Tripathi, Rakesh Tuli

Journal:

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

23

Structure–activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position

Paolo Grieco, Minying Cai, Alexander V. Mayorov, Dev Trivedi, Victor J. Hruby

Journal:

Year:

2006

Language:

english

File:

PDF, 339 KB

english, 2006

24

Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors

Minying Cai, Alexander V. Mayorov, Jinfa Ying, Magda Stankova, Dev Trivedi, Chris Cabello, Victor J. Hruby

Journal:

Year:

2005

Language:

english

File:

PDF, 144 KB

english, 2005

25

Further structure–activity studies of lactam derivatives of MT-II and SHU-9119: Their activity and selectivity at human melanocortin receptors 3, 4, and 5

Paolo Grieco, Minying Cai, Guoxia Han, Dev Trivedi, Pietro Campiglia, Ettore Novellino, Victor J. Hruby

Journal:

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

26

Solid-phase peptide head-to-side chain cyclodimerization: Discovery of C2-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors

Alexander V. Mayorov, Minying Cai, Erin S. Palmer, Zhihua Liu, James P. Cain, Josef Vagner, Dev Trivedi, Victor J. Hruby

Journal:

Year:

2010

Language:

english

File:

PDF, 625 KB

english, 2010

27

Pure Glucagon Antagonists: Biological Activities and cAMP Accumulation Using Phosphodiesterase Inhibitors

Bassem Y. Azizeh, Brian A. Van Tine, Dev Trivedi, VictorJ. Hruby

Journal:

Year:

1997

Language:

english

File:

PDF, 241 KB

english, 1997

28

Real Time Differentiation of G-Protein Coupled Receptor (GPCR) Agonist and Antagonist by Two Photon Fluorescence Laser Microscopy

Cai, Minying, Stankova, Magda, Pond, Stephanie J. K., Mayorov, Alexander V., Perry, Joseph W., Yamamura, Henry I., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 98 KB

english, 2004

29

Re-evaluation of glucagon1–6: The N-terminal hexapeptide of glucagon is not biologically active in the hepatic adenylate cyclase system

John T. Pelton, Dev Trivedi, Victor J. Hruby

Journal:

Year:

1983

Language:

english

File:

PDF, 317 KB

english, 1983

30

Effects of [1-Nα-trinitrophenylhistidine, 12-homoarginine]glucagon on cyclic AMP levels and free fatty acid release in isolated rat adipocytes

J.Adolfo García-Sáinz, Lourdes Sánchez-Sevilla, John T. Pelton, Dev Trivedi, Victor J. Hruby

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1986

Language:

english

File:

PDF, 328 KB

english, 1986

31

Design and synthesis of glucagon partial agonists and antagonists

Gysin, Beat, Trivedi, Dev, Johnson, David G., Hruby, Victor J.

Journal:

Year:

1986

Language:

english

File:

PDF, 855 KB

english, 1986

32

Metabolic effects and cyclic AMP levels produced by glucagon, (1-Nα-trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes

Corvera, Silvia, Huerta-Bahena, Judith, Pelton, John T., Hruby, Victor J., Trivedi, Dev., García-Sáinz, J.Adolfo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1984

Language:

english

File:

PDF, 559 KB

english, 1984

33

Design and Microwave-Assisted Synthesis of Novel Macrocyclic Peptides Active at Melanocortin Receptors: Discovery of Potent and Selective hMC5R Receptor Antagonists

Grieco, Paolo, Cai, Minying, Liu, Lu, Mayorov, Alexander, Chandler, Kevin, Trivedi, Dev, Lin, Guangxin, Campiglia, Pietro, Novellino, Ettore, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 930 KB

english, 2008

34

Structure−Activity Relationships of γ-MSH Analogues at the Human Melanocortin MC3, MC4, and MC5 Receptors. Discovery of Highly Selective hMC3R, hMC4R, and hMC5R Analogues

Balse-Srinivasan, Preeti, Grieco, Paolo, Cai, Minying, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

35

Substitution of Arginine with Proline and Proline Derivatives in Melanocyte-Stimulating Hormones Leads to Selectivity for Human Melanocortin 4 Receptor

Qu, Hongchang, Cai, Minying, Mayorov, Alexander V., Grieco, Paolo, Zingsheim, Morgan, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

36

Novel 3D Pharmacophore of α-MSH/γ-MSH Hybrids Leads to Selective Human MC1R and MC3R Analogues †

Cai, Minying, Mayorov, Alexander V., Cabello, Christopher, Stankova, Magda, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 513 KB

english, 2005

37

Novel Cyclic Templates of α-MSH Give Highly Selective and Potent Antagonists/Agonists for Human Melanocortin-3/4 Receptors

Kavarana, Malcolm J., Trivedi, Dev, Cai, Minying, Ying, Jinfa, Hammer, Matthew, Cabello, Christopher, Grieco, Paolo, Han, Guoxia, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 73 KB

english, 2002

38

Structure–Activity Relationships of Cyclic Lactam Analogues of α-Melanocyte-Stimulating Hormone (α-MSH) Targeting the Human Melanocortin-3 Receptor

Mayorov, Alexander V., Cai, Minying, Palmer, Erin S., Dedek, Matthew M., Cain, James P., Van Scoy, April R., Tan, Bahar, Vagner, Josef, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 995 KB

english, 2008

39

Development of Potent Truncated Glucagon Antagonists

Ahn, Jung-Mo, Medeiros, Matthew, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

40

Structure−Activity Relationships of Novel Cyclic α-MSH/β-MSH Hybrid Analogues That Lead to Potent and Selective Ligands for the Human MC3R and Human MC5R

Balse-Srinivasan, Preeti, Grieco, Paolo, Cai, Minying, Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 61 KB

english, 2003

41

A New Approach to Search for the Bioactive Conformation of Glucagon: Positional Cyclization Scanning

Ahn, Jung-Mo, Gitu, Peter M., Medeiros, Matthew, Swift, Jennifer R., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

42

Structure−Function Studies on Positions 17, 18, and 21 Replacement Analogues of Glucagon: The Importance of Charged Residues and Salt Bridges in Glucagon Biological Activity †

Sturm, Noel S., Lin, Ying, Burley, Stephen K., Krstenansky, John L., Ahn, Jung-Mo, Azizeh, Bassem Y., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 83 KB

english, 1998

43

Development of Cyclic γ-MSH Analogues with Selective hMC3R Agonist and hMC3R/hMC5R Antagonist Activities

Mayorov, Alexander V., Cai, Minying, Chandler, Kevin B., Petrov, Ravil R., Van Scoy, April R., Yu, Zerui, Tanaka, Dustin K., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 232 KB

english, 2006

44

Conformational considerations in the design of a glucagon analog with increased receptor binding and adenylate cyclase potencies

Krstenansky, John L., Trivedi, Dev., Johnson, David., Hruby, Victor J.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 443 KB

english, 1986

45

Design, Synthesis, and Biological Evaluation of New Cyclic Melanotropin Peptide Analogues Selective for the Human Melanocortin-4 Receptor

Ying, Jinfa, Gu, Xuyuan, Cai, Minying, Dedek, Matthew, Vagner, Josef, Trivedi, Dev B., Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

46

Synthesis of two glucagon antagonists: receptor binding, adenylate cyclase, and effects on blood plasma glucose levels

Gysin, Beat, Johnson, David G., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 991 KB

english, 1987

47

Receptor binding and adenylate cyclase activities of glucagon analogs modified in the N-terminal region

McKee, Roberta L., Pelton, John T., Trivedi, Dev, Hruby, Victor J., Sueiras-Diaz, Javier, Coy, David H.

Journal:

Year:

1986

Language:

english

File:

PDF, 917 KB

english, 1986

48

The Role of Phenylalanine at Position 6 in Glucagon's Mechanism of Biological Action: Multiple Replacement Analogues of Glucagon

Azizeh, Bassem Y., Ahn, Jung-Mo, Caspari, Rael, Shenderovich, Mark D., Trivedi, Dev, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 224 KB

english, 1997

49

Importance of the 10-13 region of glucagon for its receptor interactions and activation of adenylate cyclase

Krstenansky, John L., Trivedi, Dev, Hruby, Victor J.

Journal:

Year:

1986

Language:

english

File:

PDF, 923 KB

english, 1986

50

Topographical Amino Acid Substitution in Position 10 of Glucagon Leads to Antagonists/Partial Agonists with Greater Binding Differences

Azizeh, Bassem Y., Shenderovich, Mark D., Trivedi, Dev, Li, Guigen, Sturm, Noel S., Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 225 KB

english, 1996